Fmoc-8-amino-3,6-dioxaoctanoic acid是一种可裂解的 ADC 连接剂,用于合成抗体-药物偶联物。它也是一种基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。
产品描述
Fmoc-8-amino-3,6-dioxaoctanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
体外活性
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Cas No.
166108-71-0
分子式
C21H23NO6
分子量
385.41
别名
Fmoc-NH-PEG2-CH2COOH;[2-[2-(Fmoc-氨基)乙氧基]乙氧基]乙酸
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years