m-PEG12-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
m-PEG12-acid is a PEG-based PROTAC linker. m-PEG12-acid can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
2135793-73-4
分子式
C26H52O14
分子量
588.68
别名
十一乙二醇单甲醚丙酸
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years