Pentaethylene glycol di(p-toluenesulfonate) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker. Pentaethylene glycol di(p-toluenesulfonate) can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
41024-91-3
分子式
C24H34O10S2
分子量
546.65
别名
Penta(ethylene glycol) bis(p-toluenesulfonate);二对甲苯磺酸戊乙二醇;Bis-Tos-PEG5
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years