Cbz-NH-PEG1-CH2COOH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
Cas No.
1260092-43-0
分子式
C12H15NO5
分子量
253.25
别名
苄氧羰基聚乙二醇乙酸
储存和溶解度
DMSO:100 mg/mL (394.87 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years