Biotin-PEG4-Amide-C6-Azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1006592-62-6
分子式
C27H49N7O7S
分子量
615.79
别名
生物素-四聚乙二醇-氨基-C6-叠氮
储存和溶解度
DMSO:100 mg/mL (162.39 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years