Val-Cit-PAB-MMAE 是 ADC 的药物-接头偶联物。它包含 ADC 接头(肽 Val-Cit-PAB)和有效的微管蛋白抑制剂 MMAE。
产品描述
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization[1].
Cas No.
644981-35-1
分子式
C58H94N10O12
分子量
1123.43
储存和溶解度
DMSO:49 mg/mL (43.61 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years