Boc-NH-PEG12-CH2CH2COOH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1415981-79-1
分子式
C32H63NO16
分子量
717.84
别名
叔丁氧羰基十二聚乙二醇羧乙基
储存和溶解度
DMSO:100 mg/mL (139.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years