Diethylene glycol bis(p-toluenesulfonate) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
Cas No.
7460-82-4
分子式
C18H22O7S2
分子量
414.49
别名
Bis-Tos-PEG2;二乙二醇双对甲苯磺酸酯;Diethylene glycol di(p-toluenesulfonate)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years