Tetraazine-Ph-NHCO-C3-NHS 酯是一种基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。
产品描述
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1244040-64-9
分子式
C18H18N6O5
分子量
398.37
储存和溶解度
DMSO:95 mg/mL (238.47 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years