产品描述
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).
体外活性
QCA570 inhibits cell growth in MV4;11, MOLM-13, and RS4;11 cell lines (IC50: 8.3, 62, and 32 pM, respectively). QCA570 is an extremely effective and highly efficacious BET degrader, capable of degrading BET proteins at low picomolar (pM) concentrations in leukemia cells. [1].
Cas No.
2207569-08-0
分子式
C39H33N7O4S
分子量
695.79
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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