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Argireline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Argireline图片
CAS NO:616204-22-9
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
50 mg电议
100 mg电议

产品名称
阿基瑞林
六胜肽
Acetyl hexapeptide-3
产品介绍
Argireline 是可渗透皮肤的、无毒的抗皱肽。它对神经肌肉接头处依赖 Ca2+的神经递质释放具有显著的抑制作用。它具有抗皱和抗衰老的活性。

产品描述

Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3].

体外活性

The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Argireline in low concentration do not affect cell proliferation[2].

体内活性

Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased (P< 0.01), while that of type III collagen fibers decreased (P< 0.05). Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin[3].

Cas No.

616204-22-9

分子式

C35H62N14O11S

分子量

887.03

别名

阿基瑞林;六胜肽;Acetyl hexapeptide-3

储存和溶解度

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years