Laninamivir octanoate是一种长效流感神经氨酸酶抑制剂,是Laninamivir 的前药, 具有优异的抗流感病毒活性。
产品描述
Laninamivir octanoate is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.
体外活性
CS-8958 shows inhibitory activity with an IC50 of 631-1170 nM, 39.2-221 nM and 128 nM to the H1N1 viruses strains, H3N2 viruses strains and H2N2 (A/Singapore/1/57) virus, respectively[1].
体内活性
CS-8958(95 μg/kg;?intranasal administration;?three dose;?at 4 h before and 4 h and 17 h postinfection) treatment shows significantly life-prolonging effect in infected model[1].
Cas No.
203120-46-1
分子式
C21H36N4O8
分子量
472.539
别名
CS-8958;辛酸拉尼米韦
储存和溶解度
DMSO:100 mg/mL (211.63 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years