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COX-2-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
COX-2-IN-2图片
CAS NO:134729-13-8
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议

产品介绍
COX-2-IN-2 是选择性的,诱导型的 COX2 抑制剂,IC50 值为0.24 μM。COX-2-IN-2 是具有抗炎和止痛活性的抗炎物。

产品描述

COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities

体外活性

COX-2-IN-2 shows no COX-1 inhibition even at 100μM[1].

体内活性

COX-2-IN-2 has oral ED50 values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30 value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity[1].

Cas No.

134729-13-8

分子式

C17H12FN3O2S

分子量

341.36

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years