ML418 是可透过血脑屏障的钾离子通道Kir7.1选择性阻滞剂,IC50值为 310 nM。它有效抑制Kir6.2/SUR1,对 Kir7 的选择性高于其他 Kir 通道。
产品描述
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
Cas No.
1928763-08-9
分子式
C19H24ClN3O3
分子量
377.87
储存和溶解度
DMSO:20 mg/mL (52.93 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years