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Hydroquinine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hydroquinine图片
CAS NO:522-66-7
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
氢化奎宁
dihydroquinine
产品介绍
Hydroquinine 是金鸡纳生物碱,可用于制备衍生物(如 C9 脱氢喹啉、9-乙酰氧基-10,11-二氢喹、 10,11-二氢喹单盐酸盐等)。

产品描述

Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.

体内活性

Compared with placebo the decrease in the mean number of muscle cramps (16.1 or 58%) in the active drug treatment group during the medication period was highly significant (Wilcoxon test p = 0.004).Daily dose of 300 mg hydroquinine hydrobromide was effective in preventing frequent ordinary muscle cramp in healthy female volunteers. The effects of hydroquinine outlasted its administration. The drug was well tolerated.

动物实验

Twenty healthy adult volunteers experiencing at least 3 muscle cramps a week (6 men, 14 women aged 38-78 yrs) were enrolled into this study, and 19 of them completed it. Hydroquinine hydrobromide (300 mg/day) was administered to group 1 (10 women) and placebo to group 2 (4 women, 6 men). The frequency, severity, duration and location of muscle cramps as well as short-term adverse drug effects were recorded in daily diaries.

Cas No.

522-66-7

分子式

C20H26N2O2

分子量

326.43

别名

氢化奎宁;dihydroquinine

储存和溶解度

DMSO:65 mg/mL (199.12 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years