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Coryneine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:7224-66-0
包装与价格:
包装价格(元)
20 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Trimethyl(3,4-dihydroxyphenethyl)aminium
2-(3,4-dihydroxyphenyl)ethyl-trimethylazanium
棍掌碱
Dopamine methiodide
Quaternary dopamine
产品介绍
Coryneine 是从附子根中提取的多巴胺的季铵衍生物。

产品描述

Coryneine is a quaternary ammonium derivative of dopamine derived from aconite root.

体内活性

Coryneine (20-150 microM) blocked the nerve-evoked twitch response without affecting the contraction evoked by electrical stimulation of the muscle[1]. Coryneine (20 microM-2mM) itself depolarized the endplate membrane and this effect was reversibly suppressed by 1 and 5 microM pancuronium[1]. Coryneine 30 microM-10mM) produced contractions of denervated muscles in a concentration-dependent manner and the effects were reduced by 70nM pancuronium[1].

Cas No.

7224-66-0

别名

Trimethyl(3,4-dihydroxyphenethyl)aminium;2-(3,4-dihydroxyphenyl)ethyl-trimethylazanium;棍掌碱;Dopamine methiodide;Quaternary dopamine

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years