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hydrocotarnine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:550-10-7
包装与价格:
包装价格(元)
10 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
hydrocotarnine 是 Cbl 的抑制剂。

产品描述

hydrocotarnine is an inhibitor of Cbl.

体内活性

In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis. Together, our novel findings provide new insights into the role of the SFK-Cbl axis in suppressing NLRP3 inflammasome activation and identify a novel clinical utility of hydrocortanine for disease treatment[2].

Cas No.

550-10-7

分子式

C12H15NO3

分子量

221.25

储存和溶解度

DMSO:55 mg/ml (248.59 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years