Sodium cAMPtothecin 是一种植物生物碱，具有抗肿瘤活性。它是可逆 RNA 合成抑制剂，可以抑制腺病毒的复制。它能抑制 DNA 合成，并引起细胞内预形成的病毒 DNA 断裂。

Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.

Sodium Camptothecin (5 μM; 10 min) causes a severe inhibition of heterogeneously sedimenting nuclear RNA (HnRNA) synthesis [1]. Sodium Camptothecin also blocks a specific step in the processing of ribosomal precursor RNA, allowing the conversion of 45S RNA to 32S RNA while inhibiting the conversion of 32S RNA to 28S RNA [1].

25387-67-1

C20H18N2NaO5

389.36

DMSO:40mg/mL (102.73mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years