Furagin是nitrofurantoin类似物,有抗菌活性,用于尿路感染。
产品描述
Furagin is a Nitrofuran derivative with anti-infective activity used for urinary tract infections.
体外活性
The furagin concentrations in serum remain several hours above the MIC concentrations of many pathogenic bacteria. Despite the high concentrations in serum, the urine levels of furagin were generally lower than those of nitrofurantoin. The 24 hr recoveries in urine were 8--13% for furagin and about 36% for nitrofurantoin.
体内活性
A time-independent increase in SCE frequency was found in lymphocytes of children treated with furagin. Total CA frequency did not differ significantly between groups of children with various duration of furagin treatment.
Cas No.
1672-88-4
分子式
C10H8N4O5
分子量
264.197
别名
F-35;呋喃烯啶;NF-416;Furazidine;Furazidin;Akritoin
储存和溶解度
DMSO:33 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years