Alendronic acid 是法呢基二磷酸合酶(FDPS)抑制剂,是一种双膦酸盐。它能够抑制破骨细胞介导的骨吸收,对绝经后骨质疏松症,恶性高钙血症和 Paget 病具有疗效。
产品描述
Alendronic acid is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
体内活性
Alendronic Acid in the treatment of osteoporosis in children and adolescents[1].
Cas No.
66376-36-1
分子式
C4H13NO7P2
分子量
249.1
别名
alendronate;阿仑膦酸
储存和溶解度
H2O:5mg/mL
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years