BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI),EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合,对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。
产品描述
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).
体外活性
BVDV-IN-1?has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC). It is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp.
Cas No.
345651-04-9
分子式
C20H22N4O
分子量
334.423
储存和溶解度
DMSO:250 mg/mL (747.59 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years