Hydroxyprogesterone caproate 是一种甾体,是一种人工合成的孕激素。
产品描述
Hydroxyprogesterone Caproate is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
体内活性
Hydroxyprogesterone caproate is administered to pregnant rats in order to assess the effect of intraperitoneal exposure to supranormal levels of hydroxyprogesterone caproate on the male reproductive potential in the first generation. The cauda epididymal sperm count and motility decrease significantly in rats exposed to hydroxyprogesterone caproate during embryonic development, when compared with control rats. The levels of serum testosterone decrease with an increase in follicle stimulating hormone and luteinizing hormone in adult rats exposed to hydroxyprogesterone caproate during the embryonic stage[2].
Cas No.
630-56-8
分子式
C27H40O4
分子量
428.613
别名
己酸孕酮;Primolut Depot;17α-Hydroxyprogesterone caproate;17α-Hydroxyprogesterone hexanoate;Delalutin;Hormofort
储存和溶解度
H2O:<1 mgml
Ethanol:79 mg/mL (184.3 mM)
DMSO:79 mg/mL (184.3 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years