SC-26196 是一种 Delta6 去饱和酶 (D6D, FADS2) 抑制剂 (在大鼠肝微粒体中，IC50=0.2 μM)，具有口服活性，具有抗炎作用。

SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.

The FADS2 inhibitor SC26196 reduced PBMC, but not Jurkat cell, proliferation suggesting PUFA synthesis is involved in regulating mitosis in PBMCs[1].

218136-59-5

C27H29N5

423.55

ALPHA,ALPHA-二苯基-4-[(3-吡啶亚甲基)氨基]-1-吡嗪戊腈

DMSO:4mg/ml (9.44 Mm),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years