Saprorthoquinone is a natural product from Salvia prionitis.

Ten diterpenoids [6a-hydroxysalvinolone (1 ), 6a-hydroxytaxodone (2 ), aethiopinone (3 ), microstegiol (4 ), ferruginol (5 ), Saprorthoquinone (6 ), 11,12-dioxoabieta-8,13-diene (7 ), taxodione (8 ), hypargenin A (9 ), hypargenin D (10 )] and three triterpenoids [lupeol 3-acetate, d-oleanol 3-acetate and -sitosterol] were isolated from the roots of Salvia hypargeia , a plant endemic to Turkey. METHODS AND RESULTS: The crude extract and compounds 1-2 , 5-10 were tested against a panel of human cancer cell lines [human breast cancer (BC 1), human lung cancer (LU 2), human colon cancer (COL 2), human epidermoidal carcinoma in mouth (KB), vinblastine-resistant KB-VI, hormone-dependent human prostate cancer (LNCaP)] as well as P388 and ASK cells in culture. CONCLUSIONS: The crude extract was active in all of the test systems, except KB. Isolates 1 and 8 were also found to mediate a generalized cytotoxic response.

102607-41-0

C20H24O2

296.4

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years