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Crenulatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Crenulatin图片
CAS NO:63026-02-8
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍

产品描述

Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L group, respectively; the mechanism is related to the alterations of Fas/Bcl-2 expression and caspase-3 activity.

体外活性

The following terminal concentrations of Crenulatin were used in the study: 25 mg/L and 100 mg/L. Apoptosis of mouse cerebral microvascular endothelial cells (bEnd. 3 cell line) was evaluated by flow cytometer, immunocytochemical assay (Fas, Bcl - 2) and Western blotting (caspase - 3) after culture for 24 h. Compared with control group, apoptosis of bEnd. 3 cells in 25 mg/L group was significantly inhibited ( P

Cas No.

63026-02-8

分子式

C11H20O6

分子量

248.27

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years