Caracemide 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。

Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.

Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site[1].

After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine[2].

81424-67-1

C6H11N3O4

189.17

卡醋胺;NSC-253272

DMSO:95 mg/mL (502.19 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years