5-HT1A/5-HT7受体拮抗剂（5-HT1A Ki=8 nM，Kb=0.04 nM；5-HT7 Ki=451 nM，Kb=460 nM）具有PDE4B/PDE7A抑制活性（PDE4BIC50=80.4μM；PDE7AIC50=151.3μM），其抗抑郁样作用强于作为参考药物的依西酞普兰。

5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with PDE4B/PDE7A inhibitory activity (PDE4B IC 50 = 80.4 μM; PDE7A IC 50 = 151.3 μM), its antidepressant like effect is stronger than that of escitalopram as a reference drug.

C25H35N3O2

409.56

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years