FR122047 hydrochloride 是一种口服有活性的、选择性的 COX-1 抑制剂(IC50:28 nM)。它在体内具有镇痛、抗炎、抗血小板的功能。
产品描述
FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
Cas No.
130717-51-0
分子式
C23H26ClN3O3S
分子量
459.99
别名
1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride;FR 122047盐酸盐;4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
储存和溶解度
DMSO:4 mg/mL(8.70 mM)
H2O:2 mg/mL(4.35 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years