Oxaceprol 是一种可口服的、具有显著抗炎作用的 L-脯氨酸衍生物,常用于研究骨关节炎和类风湿性关节炎。
产品描述
Oxaceprol is an established therapeutic agent for osteoarthritis.
体内活性
Oxaceprol, an established therapeutic agent for osteoarthritis, had no effect on macrophage prostaglandin E2 release in vitro and inhibited carrageenan paw oedema at high doses (18-150 mg/kg p.o.).?In the same dose range, oxaceprol was comparable to indomethacin (3 mg/kg p.o.) as an inhibitor of yeast hyperalgaesia and at 6-50 mg/kg/day p.o. had a mild, variable inhibitory effect on cotton pellet granuloma formation[1]
Cas No.
33996-33-7
分子式
C7H11NO4
分子量
173.17
别名
N-Acetyl-L-hydroxyproline;奥沙西罗;N-乙酰-L-4-羟基脯氨酸
储存和溶解度
DMSO:100 mg/mL (577.47 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years