Bax inhibitor peptide V5 acetate(579492-81-2 free base) 是一种 Bax 介导的细胞凋亡抑制剂，用于癌症治疗。

Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.

Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) decreases cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells.[1]. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[2].

Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model[2].

T10463L

C29H54N6O8S

646.85

Bax inhibitor peptide V5 acetate（579492-81-2 free base)

DMSO:100 mg/mL (170.42 mM)
H2O:100 mg/mL (170.42 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years