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GLP-1(32-36)amide acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GLP-1(32-36)amide acetate图片
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
GLP-1(32-36)amide 醋酸盐
GLP-1(32-36)amide acetate(1417302-71-6 Free base)
产品介绍
GLP-1(32-36)amide acetate是一种五肽,衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。

产品描述

GLP-1(32-36)amide acetate is a pentapeptide and derived from the C terminus of the glucoregulatory hormone GLP-1. GLP-1(32-36)amide acetate could inhibit weight gain and modulate whole body glucose metabolism in diabetic mice.

体外活性

GLP-1(32-36)amide acetate (0.1-10 μM; 24 h) retains cell viability and decreases apoptosis against Streptozotocin (STZ; 1 μM) in INS‐1 cells[1].

体内活性

GLP-1(32-36)amide acetate(1 μmol/kg; i.p. once daily for 21 d) protects islet from damage, inhibits weight gain, and relieves symptoms of polydipsia in diabetic mice[1].GLP-1(32-36)amide acetate(1 μmol/kg; a single i.p.) slightly reduces the mean glucose lever at 30 min after the challenge of glucose in normal mice[1]. GLP-1(32-36)amide acetate(50-70 nmol/kg/d; infusion for 12-16 weeks) prevents the development of diet-induced obesity and hepatic steatosis in high fat-fed mice[2].

分子式

C27H54N10O7

分子量

630.78

别名

GLP-1(32-36)amide 醋酸盐;GLP-1(32-36)amide acetate(1417302-71-6 Free base)

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years