CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).

CCK-B Receptor Antagonist 2 (0.1 μmol/kg; i.v.) has an inhibition effect on pentagastrin-induced gastric acid secretion in anesthetized rats (ED50: 8.3 nmol/kg).

155412-88-7

C27H28N6O3

484.55

DMSO:250 mg/mL (515.94 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years