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Proglumide hemicalcium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Proglumide hemicalcium图片
CAS NO:85068-56-0
包装与价格:
包装价格(元)
100 mg电议
500 mg电议

产品介绍

产品描述

Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.

体外活性

in vitro, Proglumide at concentrations between 0.3-10 mM inhibits CCK-stimulated amylase release dose-dependently, while Proglumide does not influence the basal amylase release at concentrations between 0-3 mM. Dose-response curves to CCK for amylase release shifted to the right with increase in Proglumide concentration. This inhibition by Proglumide is reversible. In addition, the effect of Proglumide is selective for CCK and its related peptide[2].

体内活性

Proglumide treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1].

Cas No.

85068-56-0

分子式

C18H26CaN2O4

分子量

374.49

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years