Diethylmaleate 是马来酸二乙酯和一种抑制 NF-kB 的谷胱甘肽消耗化合物。
产品描述
Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
体外活性
Diethylmaleate and iodoacetate in combination caused augmented damage to astrocytes in a time- and concentration-dependent manner[1].
体内活性
In TR- rats, in spite of a dilatation of the Golgi apparatus and of the endoplasmic reticulum. It is unlikely that the alterations in the Golgi apparatus (and the endoplasmic reticulum) induced by diethylmaleate play a role in the canalicular secretion of diethylmaleate.
Cas No.
141-05-9
分子式
C8H12O4
分子量
172.18
别名
DIETHYL MALEATE;Maleic acid, diethyl ester;马来酸二乙酯
储存和溶解度
DMSO:60 mg/ml (348.47 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years