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Glibornuride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glibornuride图片
CAS NO:26944-48-9
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Glibornuride 是对 ATP 敏感的 K+通道 (KATP通道) 阻滞剂,pKi为 5.75。Glibornuride显示抗糖尿病活性。

产品描述

Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75). Glibornuride inhibits high affinity [3H]-glibenclamide binding with the potencies expected from their K+ channel activity.

体内活性

Administration of Glibornuride (5 mg/kg; gavage, daily for 28 days) results in an enhance in body weights in the diabetic groups in Swiss albino rats. Administration of Glibornuride for 28 days, obviously enhances the liver lipid peroxidation levels in diabetic rats. Treatment with Glibornuride (28 days) reduces serum uric acid levels in diabetic rats [2].

Cas No.

26944-48-9

分子式

C18H26N2O4S

分子量

366.48

储存和溶解度

DMSO:250 mg/mL (682.17 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years