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LEP(116-130)(mouse)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LEP(116-130)(mouse)图片
CAS NO:258276-95-8
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品介绍
LEP(116-130)(mouse) 是合成的瘦素肽片段之一。

产品描述

Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis.

体外活性

LEP-(116-130) (300 μM) is unable to inhibit AP-OB binding. Moreover, LEP-(116-130) was unable to activate signal transduction by OB-Rb in vitro[1].

体内活性

LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake than vehicle-injected control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].

Cas No.

258276-95-8

分子式

C64H109N19O24S

分子量

1560.75

储存和溶解度

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years