PI-55 是特异性细胞分裂素受体抑制剂。PI-55 在结构上与 6-benzylaminopurine (BAP) 相关,并被证明能竞争性地抑制 BAP 与拟南芥特异性受体 CRE1/AHK4 和 AHK3 的结合。PI-55 抑制细胞分裂素诱导的寄生植物吸器的形成和侵袭性的增加。
产品描述
PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins-induced haustorium formation and increased parasite aggressiveness [1].
体外活性
The high concentrations (10 μM and 100 μM) of PI-55 lead to an incomplete blocking of early haustorial structure development, especially when cytokinin activity promotes it. PI-55 treatment also reduces the overall aggressiveness of P. ramosa when applied with BAP in comparison with BAP alone, suggesting that the signaling pathway leading to early haustorial structure formation involves histidine kinase receptors homologous to CRE1/AHK4 and AHK3 [1].
Cas No.
1122579-42-3
分子式
C13H13N5O
分子量
255.28
别名
6-(2-hydroxy-3-methylbenzylamino)purine
储存和溶解度
DMSO:11.7mg/mL (45.8mM),ultrasonic and warming and heat to 70°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years