Salcaprozate sodium 是口服吸收促进剂，有作为口服形式的肝素和胰岛素递送剂的潜力。它可提高非共价大分子络合引起的亲脂性，从而增加小肠上皮细胞的被动跨细胞渗透。

Salcaprozate sodium is an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. It could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation.

Salcaprozate sodium(SNAC ;12.5-400 μg/mL;?24 h) has no toxicity to Caco-2 cells, and the survival percentage is above 90% when SNAC is 200 μg/mL.?SNAC (50 and 200 μg/mL) improves the apparent permeability coeffcient (Papp) of RA and SA-B by 2.14-fold and 3.68-fold compared with the Papp of SAs solution[1].

203787-91-1

C15H20NNaO4

301.318

8-(2-羟基苯甲酰胺基)辛酸钠;SNAC

DMSO:100 mg/mL (331.88 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years