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Dithranol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1143-38-0
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
蒽林
Anthralin
cignoline
1,8,9-trihydroxyanthracene
产品介绍
Dithranol 是蒽醌衍生物,可破坏线粒体功能和结构,用于治疗皮肤病。

产品描述

Anthralin is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.

激酶实验

THP-1 and HEK293 cells are transiently transfected using DEAE-dextran and Polyfect reagent, respectively. Plasmids transfected contain genes coding for the NF-κB-dependent pELAM-luc luciferase reporter, TLR2, TLR4, CD14, and MD2. Cells (5×105 THP-1 or 1×105 HEK293) are added to 12-well plates, washed after 18 h, and stimulated for 5 h. Cells are then lysed with reporter lysis buffer as directed, and lysates are analyzed for luminescence using Promega luciferase substrate and a Monolight 3010 luminometer.

Cas No.

1143-38-0

分子式

C14H10O3

分子量

226.23

别名

蒽林;Anthralin;cignoline;1,8,9-trihydroxyanthracene

储存和溶解度

DMSO:10 mM
Chloroform:41 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years