VPC-80051 是一种有效的 hnRNP A1 剪接活性抑制剂，靶向 hnRNP A1 RBD 并降低 22Rv1 CRPC 细胞系中的 AR-V7 信使水平。
产品描述
VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.
体外活性
VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line.
Cas No.
877969-69-2
分子式
C16H13F2N3O
分子量
301.29
别名
VPC-80051 racemate
储存和溶解度
DMSO:55 mg/ml (182.55 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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