Tilmicosin是一种抗生素,可研究曼氏杆菌和巴氏杆菌相关的牛羊呼吸系统疾病。
产品描述
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
体内活性
After a subcutaneous injection, tilmicosin is eliminated more slowly from serum and milk, with t1/2 beta S of 29.3 and 41.4 hours, respectively. The apparent volume of distribution of tilmicosin is more than 1 L/kg. The peak serum tilmicosin concentration is 1.56 μg/mL. 6.39 hours after a subcutaneous injection of 10 mg/kg. Tilmicosin is extensively secreted into milk, reaching a maximum concentration of 11.6 μg/mL and having a large AUCmilk/AUCserum ratio of approximately 12:1. Tilmicosin is detectable in milk for 11 days after a single subcutaneous dose.[2]
Cas No.
108050-54-0
分子式
C46H80N2O13
分子量
869.13
别名
替米考星;LY-177370;EL-870;Tilmicosin
储存和溶解度
Ethanol:<1 mgml
H2O:8 mg/mL (9.2 mM)
DMSO:93 mg/mL (107 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years