D-Galactosamine HCl 是一种被证实的实验毒素,它能够产生自由基及UTP核苷酸的消耗导致肝损伤,中毒剂量会造成肾功能不全,而肾功能衰竭通常和终末期肝损伤有关。脂多糖/D-Galactosamine诱导的急性肝损伤是一种已知的暴发性肝衰竭动物模型。
产品描述
D-Galactosamine HCl hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
体内活性
In mice, D-galactosamine sensitivity is associated with endotoxin sensitivity and that the former is mediated by lymphoreticular cells, not by hepatocytes[1]
Cas No.
1772-03-8
分子式
C6H14ClNO5
分子量
215.63
别名
D-半乳糖胺盐酸盐;D-Galactosamine HCl;D-氨基半乳糖盐酸盐;D(+)-Galactosamine hydrochloride
储存和溶解度
DMSO:25mg/ml(215.63mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years