Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19. Active in vivo. Brain penetrant.

1507930-54-2

C119H212N46O26

2703.28

TAT-Gap19

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years