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Phenanthriplatin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phenanthriplatin图片
CAS NO:1416900-51-0
包装与价格:
包装价格(元)
5 mg电议
100 mg电议
500 mg电议

产品名称
cis-[Pt(NH3)2-(phenanthridine)Cl]NO3
产品介绍

产品描述

Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of Topoisomerase II Cleavage Complexes. Phenanthriplatin exhibits significantly greater activity than cisplatin and oxaliplatin. The cellular uptake of phenanthriplatin is substantially greater than that of cisplatin and pyriplatin because of the hydrophobicity of the phenanthridine ligand. Phenanthriplatin binds more effectively to 5'-deoxyguanosine monophosphate than to N-acetyl methionine, whereas pyriplatin reacts equally well with both reagents.

Cas No.

1416900-51-0

分子式

C13H15ClN4O3Pt

分子量

505.82

别名

cis-[Pt(NH3)2-(phenanthridine)Cl]NO3;Phenanthriplatin

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years