| CAS NO: | 15291-75-5 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| Molecular Weight (MW) | 408.4 |
|---|---|
| Formula | C20H24O9 |
| CAS No. | 15291-75-5 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 81 mg/mL (198.3 mM) |
| Water:<1 mg/mL | |
| Ethanol: 2 mg/mL (4.9 mM) | |
| Other info | Chemical Name: 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta(c)furo(2,3-b)furo(3',2':3,4)cyclopenta(1,2-d)furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)- InChi Key: FPUXKXIZEIDQKW-VKMVSBOZSA-N InChi Code: InChI=1S/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15+,17-,18+,19-,20-/m1/s1 SMILES Code: C[C@@H]1C(O[C@@H]2[C@@]1(O)[C@@]34C(O[C@H]5[C@@]3([C@]6([C@@H](O)C(O[C@H]6O4)=O)[C@H](C(C)(C)C)C5)C2)=O)=O |
| Synonyms | BN52020; Ginkgolide A; BN 52020; BN-52020; |
| In Vitro | In vitro activity: Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. Ginkgolide A (BN-52020) failed to affect apoptotic damage neither in serum-deprived nor in staurosporine-treated neurons |
|---|---|
| In Vivo | Ginkgolide A significantly shortened the sleeping time in anesthetized mice |
| Animal model | Mice |
| Formulation & Dosage | N/A |
| References | [1]. Wada, K., et al., Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics. Biol Pharm Bull, 1993. 16(2): p. 210-2. [2]. Ahlemeyer, B. and J. Krieglstein, Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry, 2003. 36(S 1): p. 8-14. |
m.cnreagent.com