Smurf1-IN-A01 是泛素连接酶 Smad 泛素化调节因子-1(Smurf1)抑制剂，其kd=3.664 nM。它能够抑制 Smurf1 介导的 Smad1/5 降解，并提高 BMP-2 的反应性。

Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

1007647-73-5

C22H20ClF3N4O3S

512.93

A01;Smurf1-IN-A01

DMSO:62.5 mg/mL (121.85 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years