RNAIII-inhibiting peptide TFA(228544-21-6 free base) 抑制肽(TFA)抑制金黄色葡萄球菌,对蜂窝织炎、角膜炎、化脓性关节炎、骨髓炎和乳腺炎等疾病有效。
产品描述
RNAIII-inhibiting peptide(TFA) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.
体外活性
The RNAIII inhibiting peptide (RIP) is able to inhibit S. aureus pathogenesis by disrupting QS mechanism competing with RAP, thus inhibiting the phosphorylation of TRAP. This alteration leads to a reduced adhesion and to the inhibition of RNAIII synthesis, with the subsequent suppression of toxins synthesis.
Cas No.
TP1412
分子式
C47H57F3N10O13
分子量
1027.01
别名
RNAIII-inhibiting peptide(TFA);L-酪氨酰-L-丝氨酰-L-脯氨酰-L-色氨酰-L-苏氨酰-L-天冬氨酰胺酰-L-苯丙氨酸;RNAIII-inhibiting peptide TFA
储存和溶解度
DMSO:150 mg/mL (146.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years