Gadopentetic acid 是一种顺磁性造影剂,通常通过静脉内注射 (i.v.) 的方式用于 DCE-MRI 研究。
产品描述
Gadopentetic acid (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.
体内活性
The initial concentration of Gadopentetic acid (Gd-DTPA) in the plasma ([Gd-DTPA0]) is an important parameter for DCE-MRI.?[Gd-DTPA0] is related to the administered bolus dose and varies with subjects.?A bolus of 0.025 mmol/kg Gd-DTPA offers shorter acquisition time and less exposure of subjects, with a half-life of 37.3 mins, a mean residence time of 53.8 mins, and an AUC of 3.37 ± 0.47 mmol/min/L.
Cas No.
80529-93-7
分子式
C14H19GdN3O10
分子量
546.56
别名
Gd-DTPA;gadolinium complex;钆喷酸;Gadopentetic acid
储存和溶解度
H2O:100 mg/mL (182.63 mM),Need ultrasonic
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years