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Bitertanol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bitertanol图片
CAS NO:55179-31-2
包装:5 mg
市场价:287元

产品名称
Biloxazol
联苯三唑醇
Sibutol
Baycor
KWG 0599
KWG0599
KWG-0599
产品介绍
Bitertanol 是一种三唑类杀菌剂。 Bitertanol 抑制去甲基化,破坏膜功能,并阻止甾醇合成。

产品描述

Bitertanol is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.

体内活性

Bitertanol (10, 25, and 100 mg/kg) produced 2-, 4-, and 14-fold increases of 7-ethoxyresorufin O-deethylation activity in liver microsomes, respectively. Bitertanol (25 mg/kg) increased CYP1A1 protein in the liver, kidney, and lung by 10-, 13-, and 17-fold, respectively. Bitertanol produced smaller increases of CYP2B and CYP3A catalytic activity and protein than that of CYP1A1 in liver. Additions of 0.01-100 microM Bitertanol to liver microsomes from rats Bitertanol (25 mg/kg) inhibited microsomal 7-ethoxyresorufin O-demethylation activity (IC50=0.8 microM). Bitertanol (100 mg/kg) increased liver UDP-glucuronosyltransferase and glutathione S-transferase activities by 2-fold. Bitertanol (25 mg/kg) produced a minor increase in metabolic activation of benzo[a]pyrene by liver S-9 fraction in the Ames mutagenicity test while the increase was blocked by addition of 100 microM Bitertanol[2].

Cas No.

55179-31-2

分子式

C20H23N3O2

分子量

337.42

别名

Biloxazol;联苯三唑醇;Sibutol;Baycor;KWG 0599;KWG0599;KWG-0599;Bitertanol

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years