Ammonium formate 是最简单的羧酸。它通过抑制细胞色素氧化酶活性(电子传递链的末端电子受体)来负责代谢性酸中毒和破坏线粒体电子传递和能量产生。
产品描述
Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.
Cas No.
540-69-2
分子式
CH5NO2
分子量
63.056
别名
甲酸铵;Formic acid ammonium salt;Ammonium formate
储存和溶解度
DMSO:200 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years